Clarity · Wellbeing · Control
Always
The INUPLUS® patented natural supplement — Complete partner brief (International Markets)
Confidential — please do not distribute without authorisation.
Partner Brief — Table of Contents
From product fundamentals to partnership models · A complete reference for business development
Product Overview
One 10g powder sachet · Felt in 20–30 minutes · 24-hour continuous action
ELVION PLUS is a powder supplement built around the INUPLUS® patented natural prebiotic formula, originating in Europe. The product is a natural, odourless and tasteless powder — one 10g sachet per day. Core value proposition: Clarity · Wellbeing · Control · Always — supports the liver and helps consumers return to mental clarity and physical wellbeing in just 20–30 minutes after consumption, while also serving as a daily option for long-term gut and liver care.
| Format | Natural, odourless, tasteless powder |
|---|---|
| Net Weight | 10g per sachet |
| Frequency | One sachet daily |
| Time to Feel | 20–30 minutes (trans-mucosal absorption complete; body returns to clarity and ease) |
| Full Action Duration | 24 hours (four sequential phases) |
| Standard Protocol | 10g in ~40 ml room-temperature still water → hold in mouth 20–30 sec → swallow → wait 20–30 min No cold or sparkling water. Take before drinking, after drinking, or at any time of day. |
| Core Formula | INUPLUS® prebiotic inulin + Chromium Picolinate + Vitamin B12 + Selenium |
| Origin | Europe |
| Shelf Life | (Per manufacturer COA — full technical specs available on request) |
Key Differentiators
- Common "after-drink" products on the market address only single touch-points (liver-only pills, breath-only mints); ELVION PLUS is full-pathway support — across mouth, oesophagus, stomach, gut, and liver — over 24 hours.
- The core formula is a brand-new 2024 patent, not a generic stacking of common nutrients — a true differentiated technological moat.
- All four active ingredients correspond to authoritative health function claims; messaging is fully traceable and stands up to regulatory scrutiny.
INUPLUS® Patent Technology
2024 globally exclusive patent · Multi-jurisdictional protection
INUPLUS® is a prebiotic inulin (chemically: β-(2→1) fructosylated FOS) with a specific degree of polymerisation (DP). It is the result of years of university research and was patented in 2024 with multi-jurisdictional coverage, officially described as "globally exclusive".
| Patent Number | EU 3197297 |
|---|---|
| Patent Year | 2024 |
| Coverage | EU · Switzerland · UK |
| Patent Scope | Globally exclusive (Worldwide exclusive patent) |
| R&D Background | Years of university research collaboration · International peer-reviewed literature support |
| Chemical Structure | β-(2→1) fructosylated FOS, specific DP distribution |
Three Core Properties of the Patent
① Resists Digestive Enzymes
Not hydrolysed by salivary amylases or intestinal sucrase-isomaltase; reaches the colon intact and performs full prebiotic action.
② Physically Entraps Ethanol
Forms a low-viscosity polysaccharide gel in aqueous solution; physically traps ethanol through hydrophobic interactions and hydrogen bonds, reducing effective vapour pressure.
③ Natural Micronutrient Carrier
Fructose chains create a hydration microenvironment, optimising trans-epithelial concentration gradients for B12 / Se / Cr and significantly improving absorption.
④ Specific DP Optimises Fermentation
Specific degree of polymerisation determines fermentation rate and SCFA spatial distribution along the colon — superior prebiotic effect vs. generic long-chain inulin.
Patent Moat — Commercial Value
INUPLUS® is not generic inulin — it is a patented specific formulation. Competitors cannot replicate it; agents can build genuine differentiation in their regional market through the patent shield.
Four-Phase Mechanism of Action
Within 24 hours · From mouth to gut–liver axis · Activated in anatomical sequence
ELVION PLUS acts through 4 mechanisms activated in anatomical sequence, together providing full-pathway support across 5 sites: mouth / oesophagus / stomach / gut / liver.
Facilitated Transmucosal Absorption
The sublingual mucosa is a non-keratinised multi-layered epithelium, only 100–200 µm thick, densely vascularised. INUPLUS® acts as a natural carrier — its fructose chains create a hydration microenvironment that maintains B12 / Se / Cr in free ionic form, optimising trans-epithelial concentration gradient and bypassing first-pass hepatic metabolism, significantly enhancing active-ingredient absorption efficiency.
- Key sites: sublingual mucosa · oral epithelium
- Data: B12 sublingual vs. oral bioavailability +40–60%
Ethanol Physical Entrapment & Mucosal Protection
INUPLUS® forms a low-viscosity polysaccharide gel in aqueous solution, physically entrapping ethanol molecules via weak hydrophobic interactions and hydrogen bonds, reducing effective vapour pressure. This mechanism contributes to the reduction of alcoholic halitosis and protects the oesophageal and gastric mucosa from direct irritation.
- Key sites: Mouth · Oesophagus · Gastric mucosa
Selective Colonic Fermentation & SCFA Production
Inulin reaches the colon intact and becomes the selective substrate for Bifidobacterium and Lactobacillus. Anaerobic fermentation produces short-chain fatty acids (SCFAs) in proportions of approximately: acetate (C2) ≈ 60% · propionate (C3) ≈ 25% · butyrate (C4) ≈ 15%. Butyrate is the preferred energy substrate for colonocytes, stabilises tight-junction proteins (ZO-1 / occludin / claudin), regulates epigenetics through HDAC inhibition, and modulates NFκB-mediated local inflammatory responses.
Reference: van Loo et al., 1999 · Roberfroid, 2005Gut–Liver Axis Systemic Protection & Endotoxaemia Reduction
Acute or chronic ethanol intake disrupts gut microbiota (dysbiosis): SCFA producers decrease and gram-negative LPS-producing bacteria increase. LPS travels through the portal vein to the liver, where it is recognised by TLR4 receptors on Kupffer cells, activating the NFκB pathway and producing TNF-α / IL-1β / IL-6 — the core pathway of alcoholic liver injury. INUPLUS®-derived butyrate stabilises tight junctions, reducing portal LPS translocation, attenuating TLR4 activation and alcohol-induced hepatic steatosis; propionate simultaneously supports hepatic gluconeogenesis, maintaining post-drinking glucose stability.
Reference: Cani P.D. et al., 2009 · Szabo G. & Banan A., 2010Active Ingredients & Health Claims
Every ingredient corresponds to an authoritative health function claim
All four active ingredients of ELVION PLUS are backed by health function claims reviewed by authoritative international food-safety authorities. Partners can use these descriptors with confidence — they are traceable, compliant, and require no euphemism.
| ① INUPLUS® Prebiotic Inulin | β-(2→1) fructosylated FOS at a specific degree of polymerisation · Resists digestive enzymes · Reaches the colon intact · Selectively nourishes Bifidobacterium and Lactobacillus · Reduces post-meal glycaemic peak · Produces SCFAs that nourish the intestinal barrier |
|---|---|
| ② Chromium Picolinate | Authoritative claim: Contributes to maintaining normal blood glucose levels · Supports normal insulin function · Supports normal macronutrient metabolism (carbohydrates / proteins / fats) |
| ③ Vitamin B12 (Cyanocobalamin) |
Authoritative claim:
Reduces tiredness and fatigue · Supports normal nervous system function ·
Contributes to normal psychological function · Normal red blood cell formation ·
Energy metabolism support Sublingual bioavailability +40–60% vs. oral (Sharabi 2003) |
| ④ Selenium | Authoritative claim: Protects cells from oxidative stress · Maintains normal immune function · Maintains normal thyroid function · Maintains normal hair and nail growth |
On Precise Dosages
Public-facing materials do not disclose exact mg/µg per sachet. Prior to signing, partners may request the complete TDS (Technical Data Sheet) and COA (Certificate of Analysis), including per-batch dosage data and heavy-metal/microbiological test reports.
Scientific Literature
Internationally peer-reviewed literature · Claims fully traceable
The multi-phase action model of ELVION PLUS is built on the following peer-reviewed publications from leading international academic journals. All references are publicly verifiable, giving partners a complete supporting chain when communicating with customers or regulators.
| 1 · Sharabi A. et al. (2003) | Comparative study of sublingual vs. oral Vitamin B12 bioavailability. Results showed a +40–60% increase via the sublingual route, supporting the INUPLUS® rationale as a trans-mucosal B12 carrier. |
|---|---|
| 2 · van Loo J. et al. (1999) | Fermentation rate and spatial distribution of SCFA (acetate / propionate / butyrate) production from inulin in the colon. Supports the INUPLUS® specific-DP fermentation optimisation mechanism. |
| 3 · Roberfroid M. (2005) | Definition of prebiotics; comprehensive review of inulin's mechanism in gut microbiota nourishment and resulting health benefits. Provides the academic foundation for the INUPLUS® prebiotic positioning. |
| 4 · Cani P.D. et al. (2009) | Foundational research on gut microbiota · LPS · gut–liver axis inflammation. Supports the scientific basis for INUPLUS®'s reduction of portal LPS and attenuation of the TLR4 pathway. |
| 5 · Szabo G. & Banan A. (2010) | Molecular pathway research on alcoholic liver injury (TLR4–NFκB–TNF-α/IL-1β/IL-6). Explains why alcohol damages the liver and why reducing LPS translocation is a key intervention point. |
Compliance Advantage
All function claims trace to peer-reviewed academic literature — a scientific foundation that most "after-drink" products lack entirely. When communicating with pharmacies, retail chains, or medical professionals, this is the core trust anchor.
Certifications & Compliance
Complete international compliance chain · Suitable for multiple channels
| Patent Protection | EU 3197297 · Switzerland · UK multi-jurisdictional registration (2024) |
|---|---|
| Health Function Claims | 15 · Reviewed by authoritative international food-safety authority |
| Regulatory Compliance | Compliant with EU Reg. 1169/2011 food information labelling regulation |
| Vegan Certification | Vegan |
| Allergens | Gluten-free · Lactose-free · Allergen-free |
| Natural Status | 100% natural ingredients |
| Product Format | Natural odourless and tasteless powder |
Channel Suitability
Pharmacy / Health Chains
Functional supplement positioning · Co-merchandises with gut, glycaemic, and wellness categories. Patent and literature backing match pharmacy professional discourse.
Supermarket / Premium Retail
10g single-sachet format works on health-functional category shelves; premium positioning supports a high price-point ASP.
E-commerce / Cross-border
Allergen-free + vegan attributes suit cross-border health categories; content marketing converts easily.
Hospitality / Bars / Lounges
Positionable as a value-added service for premium clients — brand differentiation and high-value-customer retention.
Local Registration Considerations
Each target market has its own health-supplement registration requirements. Partners should plan market entry according to local regulatory pathways. For markets where formal supplement registration is lengthy, common entry routes include "general food" or "cross-border e-commerce" channels for faster initial rollout.
Market Positioning
Precise entry through drinking culture & premium wellness segments
Target Audience
- Core segment: 30–55 year old upper-middle-class professionals with regular social drinking occasions, who value quality of life and personal state management. Mid-to-high price tolerance.
- Secondary segment: Urban professional women · Quality-of-life-conscious health consumers · Middle-aged and older consumers concerned with gut and liver care.
- Scenario expansion: Business dinners · Holiday family meals · Reunions with friends · Weddings · Industry galas · Festive gifting.
Four Compliant Marketing Pillars
| ① Fresh Breath After Drinking | Composure as ever · No trace left — INUPLUS physically entraps ethanol molecules (real function) |
|---|---|
| ② Stomach Comfort | No burn after drinking · Calm as before — polysaccharide gel protects the gastric mucosa |
| ③ Mental Clarity | Clear after drinking · Like nothing happened — B12 reduces fatigue / Se antioxidant / propionate maintains glucose stability |
| ④ Long-Term Liver Support | Consistent gut and liver care — SCFAs · microbiota balance · gut–liver axis |
General Marketing Cautions
- Do not use absolute language such as "prevent", "cure", "guaranteed", or "best"
- Do not make medical or therapeutic claims (e.g. "treats", "cures", "diagnoses")
- Do not claim the product enables driving after drinking or affects breathalyser results — both factually inaccurate and legally risky in most jurisdictions
- Stay within scientifically supported function-claim language reviewed by authoritative food-safety authorities
- Comply with local food/supplement advertising regulations of each target market
Recommended Messaging Framework
| ❌ Avoid | ✅ Use |
|---|---|
| Sober up / Alcohol antidote | Post-drinking ease · After-drink care · Restore mental clarity |
| Accelerate metabolism | Supports body metabolism · Aids normal carbohydrate metabolism |
| Lowers breathalyser reading | Reduces post-drinking breath odour · Stay composed |
| Prevents hangover | Eases hangover discomfort · Reduces next-day fatigue |
| Enables drink-and-drive | Wake up clear and composed the next day |
Pricing & Margin Reference
Reference pricing model based on European retail benchmarks
European Retail Reference (Benchmark)
| SKU | Format | European Retail | USD ≈ |
|---|---|---|---|
| Single Sachet | 10g × 1 | €19.90 | $21.50 |
| 3-Pack | 10g × 3 | €49.90 | $53.90 |
| Unit price (within 3-pack) | ≈ 10g | ≈ €16.63 | ≈ $17.95 |
Exchange reference €1 ≈ $1.08. Final retail price set by regional partner based on local market dynamics.
Recommended International Retail Bands (Reference)
| Channel | Suggested Single Sachet | Suggested 10-pack | Positioning |
|---|---|---|---|
| Pharmacy / Health Chains | $15–22 | $130–180 | Premium functional supplement |
| Supermarket / Premium Retail | $18–25 | $160–200 | Gift sets · Holiday |
| E-commerce / D2C | $12–18 | $110–160 | Content marketing · Repeat purchase |
| Premium Hospitality | $20–28 | — | Guest value-add service |
Partnership Margin Bands (Reference · Final terms negotiated)
| Tier | Volume Commitment | Margin Range | Support |
|---|---|---|---|
| Exclusive Regional Agent | Large annual commitment | 50–65% | Exclusivity · Full marketing kit · Training |
| Wholesale Distributor | Pallet-level MOQ | 35–50% | Standard creative · Digital support |
| E-commerce / Cross-border | Quarterly commitment | 30–45% | E-commerce kit · Cross-border compliance support |
| OEM / Co-brand | Project-based | Negotiable | Private label / Custom formulation |
Differentiated Margin Logic
Common "after-drink" mints and drinks sit at $1–4 ASP, where margins are eroded by price competition. Backed by patent, scientific literature, and premium positioning, ELVION PLUS sustains a $15+ ASP band — partner margin is materially higher than the conventional after-drink category.
Partnership Models
Four cooperation pathways for international markets
① Exclusive Regional Agency
| Target | Established agents with regional or national distribution networks |
|---|---|
| Core Rights | Regional exclusive sales rights · Price protection · Channel-conflict prevention support |
| Commitments | Annual purchase commitment · Channel rollout milestones |
| Brand Support | Full marketing kit · Sales training · Co-marketing investment · POSM |
② Wholesale Distribution
| Target | Buyers for pharmacies, supermarkets, hospitality chains |
|---|---|
| MOQ | Pallet-level (specifics negotiable) |
| Pricing Policy | Tiered wholesale pricing · Quarterly rebates |
| Brand Support | Standard creative pack · Shelf-merchandising guidance · Training materials |
③ E-commerce / Cross-border Distribution
| Target | Amazon · Independent D2C · Cross-border marketplaces · Social commerce |
|---|---|
| Policy | Cross-border compliance support · Content kit · Influencer collaboration playbook |
| Compliance Strengths | Allergen-free + vegan + patent backing — content-marketing-ready |
④ OEM / Co-branding
| Target | Health companies with existing brands · Adjacent-category co-branding |
|---|---|
| Scope | Private label · Co-branded launches · Limited formulation adjustments · Gift sets |
| Terms | Project-based quoting · Case-by-case negotiation |
Process & Contact
Five-step business engagement workflow
Standard Engagement Process
Resources Available to Partners
- Dedicated account manager · Response within 24 hours
- Complete TDS (Technical Data Sheet) and COA (Certificate of Analysis)
- Sample shipping and field testing support
- Full marketing kit (posters / videos / product pages / training materials)
- Channel training (sales playbook / compliance language / product knowledge)
- Regional exclusivity and OEM partnerships negotiable
- Priority allocation for new-product launches
Get in Touch
Business Development · Xu Haimin
| Location | Zhejiang, Wenzhou, China |
|---|---|
| WeChat Work | GCLOVER · Scan the QR (top right) |
| Phone | +86 139 5772 4595 |
| Business Email | xuluigi@yahoo.it |
Product Consultant · Easyfarma
| WeChat ID | easyfarma01 · Scan the QR (bottom right) |
|---|
| Response Time | Within 24 hours · Tailored partnership proposal |
|---|
Next Step
Connect by WeChat, phone, or email — we will provide a tailored partnership proposal based on your channel profile, geographic coverage, and volume expectations, along with sample shipping and complete technical documentation (TDS / COA).
Business Development
Product Consultant
© ELVION PLUS · INUPLUS® is a registered trademark
Document provided for partner business reference only, not medical or diagnostic advice.
Confidential · Please do not distribute without authorisation.